Impact of highly active antiretroviral therapy on hematological indices among HIV-1 infected children at Kenyatta Nation
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RESEARCH
Impact of highly active antiretroviral therapy on hematological indices among HIV‑1 infected children at Kenyatta National Hospital‑Kenya: retrospective study Elizabeth Gathoni Kibaru1,4*, Ruth Nduati2, Dalton Wamalwa2 and Nyambura Kariuki2,3
Abstract Background: HIV infected children experience a range of hematological complications which show marked improvement within 6 months of initiating anti-retroviral therapy. The Objectives of the study was to describe the changes in hematological indices of HIV-1 infected children following 6 months of treatment with first line antiretroviral drugs (ARVs) regimen. Methods: A retrospective study was conducted between September and November 2008. During this period medical records of children attending Comprehensive Care Clinic at Kenyatta National hospital were reviewed daily. HIV infected children aged 5–144 months were enrolled if they had received antiretroviral drugs for at least 6 months with available and complete laboratory results. Results: Medical records of 337 children meeting enrollment criteria were included in the study. The median age was 63 months with equal male to female ratio. Following 6 months of HAART, prevalence of anemia (Hemoglobin (Hb)
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