Influence of muscle mass on the estimation of glomerular filtration rate in Japanese terminal cancer patients
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ORIGINAL ARTICLE
Influence of muscle mass on the estimation of glomerular filtration rate in Japanese terminal cancer patients Yoshihiro Uekuzu1,2,3,4 · Takashi Higashiguchi4 · Akihiko Futamura2,4 · Takeshi Chihara5 · Masanobu Usui4 Received: 21 October 2019 / Accepted: 16 May 2020 © Japanese Society of Nephrology 2020
Abstract Background Estimated glomerular filtration rate (eGFR) based on serum cystatin C (Scys) is useful for patients with decreased muscle mass, but has been also reported to be affected by cancer. The usefulness of Scys in eGFR in terminal cancer patients with decreased muscle mass is unknown. Therefore, we analyzed appropriate eGFR formulae for terminal cancer patients. Methods Study design was a retrospective observational study. Based on creatinine height index (CHI), 184 terminal cancer patients were stratified into CHI ≥ 90% (normal muscle mass, 59 patients); CHI 60–89% (mildly to moderately decreased muscle mass, 64 patients); and CHI
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