Innovative, long-lasting and eco-friendly surface decontamination approach using modified Titania based on nanotechnolog
- PDF / 783,486 Bytes
- 5 Pages / 595.276 x 790.866 pts Page_size
- 110 Downloads / 173 Views
SHORT COMMUNICATION
Innovative, long‑lasting and eco‑friendly surface decontamination approach using modified Titania based on nanotechnology Krunal Dholiya1 Received: 10 September 2020 / Accepted: 12 November 2020 © IUPESM and Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Hospital-acquired infections (HAI), usually known as nosocomial infections, have become a major challenge and they are frequently associated with resistance to the highest priority critically important antimicrobials. In this line, the treatment of each infection can be compromised. The solid surfaces of the hospital become significant sources of transmission and lead most often to the contamination and cross-contamination of nosocomial pathogens to the patients and staff. Traditional biocides (i.e. detergent, alcohol, chloride-based and antibiotics) have limited effectiveness over time. As alternative to this sanitization approach, modified Nano TiO2 coating, was selected for this preliminary study. After applying the coat on a solid surface, it will become change to a transparent antimicrobial film. When light fall on coated particles, they generate electron–hole pairs. These generated pairs will react with moisture and oxygen from the air which generates reactive radicals with capacity to attack microbial cells and promote their death. From in vitro study, the coating is inhibiting three types of bacteria (E. coli, S. aureus, P. aeruginosa) by growing and colonizing on the solid surfaces. Nanoparticle acts constantly and is durable over time due to the activity as photocatalyst which can reduce and contain the proliferation of microorganisms. In such a scenario, Ecobactix comes as a safe and long-lasting antibacterial shield for surfaces. Modified TiO2 coating based on photocatalysis (nano Titania) is a promising, long-lasting and effective biocidal technique for disinfection surfaces, especially innovative product around the nosocomial environment. Keywords Nosocomial infection · TiO2 nanocoating · Ecobactix® · Long-lasting
1 Introduction Hospitals are responsible for providing healthcare to patients with specialized staff and advanced equipment for correct diagnosis. Antibiotic resistance and dissemination of multidrug-resistant (MDR) microorganisms are considered public health concerns, not only in human medicine but also in veterinary medicine and animal production [1–3]. Enterobacteriaceae family (including K. pneumoniae and E. coli), Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE) and Pseudomonas aeruginosa are considered MDR nosocomial organisms. These pathogens can be transmitted among humans, healthcare professionals, environment or contaminated water and food. The emergence of MDR clones containing relevant
* Krunal Dholiya [email protected]; [email protected] 1
R&D Scientist, Framtix Holdings Ab, Malmö, Sweden
resistance genes is considered an issue with public health significance. Therefore, drugs are often used to tackle this issue. AMR res
Data Loading...
