Insulin glargine
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Recurrent hypoglycaemia: case report A 56-year-old man developed recurrent hypoglycaemia while receiving insulin glargine. The man had an 8-year history of type 2 diabetes mellitus and had initially been treated with metformin and glimepiride, which did not provide adequate glycaemic control. He was then prescribed insulin glargine, given once in the evening at a starting dose of 14U [route not stated]. The dose was titrated according to self-monitored blood glucose values. At 4 months, he had increased his dose to 34U/day and had experienced recurrent hypoglycaemia [duration of treatment to reaction onset not stated]. These episodes limited further titration. He had also gained 5kg in body weight. He was switched to insulin aspart/insulin protamine aspart. At 4-month follow-up, he had achieved good glycaemic control and had not experienced any hypoglycaemic episodes. Gumprecht J. Initiation of biphasic insulin aspart in a patient failing basal insulin 803074503 treatment. European Endocrinology 7: 127-128, No. 2, 2011 - Poland
0114-9954/10/1413-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 4 Aug 2012 No. 1413
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