Intradermal Immunization

Despite the impressive success of current vaccine programs, there remains a need to improve the effectiveness of current vaccines. A more powerful and longer lasting immune response induced by smaller and fewer doses of vaccine is an exciting challenge. I

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Series Editors Klaus Aktories Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, Abt. I, Albertstr. 25, 79104 Freiburg, Germany Richard W. Compans Department of Microbiology and Immunology, Emory University School of Medicine, 3001 Rollins Research Center, Atlanta, 30322, GA, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, 30322, GA, USA Yuri Y. Gleba ICON Genetics AG, Biozentrum Halle, Weinbergweg 22, 06120 Halle, Germany Tasuku Honjo Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Sakyoku, Yoshida, Kyoto, 606-8501, Japan Hilary Koprowski Biotechnology Foundation, Inc., 119 Sibley Avenue, Ardmore, PA, 19003, USA Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288, Marseille Cedex 9, 13288, France Fritz Melchers Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany Michael B. A. Oldstone Department of Neuropharmacology, Division of Virology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA, 92037, USA

Current Topics in Microbiology and Immunology Previously published volumes Further volumes can be found at www.springer.com Vol. 325: Shenk, Thomas E.; Stinski, Mark F. (Eds.): Human Cytomegalovirus. 2008. ISBN 978-3-540-77348-1

Vol. 338: Rothman, Alan L. (Ed.): Dengue Virus. 2009. ISBN 978-3-642-02214-2

Vol. 326: Reddy, Anireddy S. N.; Golovkin, Maxim (Eds.): Nuclear pre-mRNA processing in plants. 2008 ISBN 978-3-540-76775-6

Vol. 339: Spearman, Paul; Freed, Eric O. (Eds.): HIV Interactions with Host Cell Proteins. 2009. ISBN 978-3-642-02174-9

Vol. 327: Manchester, Marianne; Steinmetz Nicole F. (Eds.): Viruses and Nanotechnology. 2008. ISBN 978-3-540-69376-5 Vol. 328: van Etten, (Ed.): Lesser Known Large dsDNA Viruses. 2008. ISBN 978-3-540-68617-0 Vol. 329: Griffin, Diane E.; Oldstone, Michael B. A. (Eds.): Measles. 2009 ISBN 978-3-540-70522-2 Vol. 330: Griffin, Diane E.; Oldstone, Michael B. A. (Eds.): Measles. 2009. ISBN 978-3-540-70616-8 Vol. 331: Villiers, E. M. de (Ed.): TT Viruses. 2009. ISBN 978-3-540-70917-8 Vol. 332: Karasev A. (Ed.): Plant produced Microbial Vaccines. 2009. ISBN 978-3-540-70857-5 Vol. 333: Compans, Richard W.; Orenstein, Walter A. (Eds.): Vaccines for Pandemic Influenza. 2009. ISBN 978-3-540-92164-6

Vol. 340: Saito, Takashi; Batista, Facundo D. (Eds.): Immunological Synapse. 2010. ISBN 978-3-642-03857-0 Vol. 341: Bruserud, Øystein (Ed.): The Chemokine System in Clinical and Experimental Hematology. 2010. ISBN 978-3-642-12638-3 Vol. 342: Arvin, Ann M. (Ed.): Varicella-zoster Virus. 2010. ISBN 978-3-642-12727-4 Vol. 343: Johnson, John E. (Ed.): Cell Entry by Non-Enveloped Viruses. 2010. ISBN 978-3-642-13331-2 Vol. 344: Dranoff,