Introduction to Skin Biothermomechanics and Thermal Pain

"Introduction to Skin Biothermomechanics and Thermal Pain" introduces the study of coupled bio-thermo-mechanical and neural behavior of skin tissue in response to thermal and mechanical loads. The research in this book focuses on the theoretical modeling

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Introduction to Skin Biothermomechanics and Thermal Pain

Feng Xu Tianjian Lu

Introduction to Skin Biothermomechanics and Thermal Pain With 126 figures

Authors Feng Xu Brigham Women’s Hospital Harvard Medical School Harvard University Cambridge, MA, 02139, USA Email: [email protected]

Tianjian Lu School of Aerospace Xi’an Jiaotong University Xi’an, Shaanxi, 710049, China Email: [email protected]

ISBN 978-7-03-027077-1 Science Press Beijing ISBN 978-3-642-13201-8 e-ISBN 978-3-642-13202-5 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2010927408 © Science Press Beijing and Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: Frido Steinen-Broo, EStudio Calamar, Spain Printed on acid-free paper Springer is a part of Springer Science+Business Media (www.springer.com)

Preface Advances in laser, microwave and similar technologies in medicine have led to recent developments of thermal treatments for disease and injury, involving skin tissue. In spite of the widespread use of thermal therapies in dermatology, they do not draw upon the detailed understanding of the biothermomechanical-neurophysiological behaviour, for none exists to date, even though each behavioural facet is somewhat established and understood. In view of this dilemma, a new research area emerges, which is the subject of this book: “Introduction to Skin Biothermomechanics and Thermal Pain”. This area is highly interdisciplinary, involving the subjects of engineering, biology and neurophysiology. This book is focused on the introduction of this new research area. According to the schematic relationship between the areas involved, this book is divided into four parts: PART I. Skin bioheat transfer and thermal damage; PART II. Skin biomechanics; PART III. Skin biothermomechanics; PART IV. Skin thermal pain. The book is multidisciplinary with a market across several subject areas and will be interesting to a wide range of readers from lab bench to clinics. The book is primarily planed as a textbook and reference book. It targets three segments of readers: (1) Advanced students: this book primarily aimed at advanced graduate students in bioengineering, who have alr