Late cutaneous metastases to the face from malignant pleural mesothelioma: A case report and review of the literature
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Case report
Late cutaneous metastases to the face from malignant pleural mesothelioma: A case report and review of the literature Alaaeldeen M Elbahaie*1, Dia E Kamel2, Julia Lawrence3 and Neville G Davidson1 Address: 1Clinical Oncology Department, Mid Essex Hospital Services NHS Trust, Broomfield Hospital, Court Road, Chelmsford, CM1 7ET, UK, 2Histopathology Department, Mid Essex Hospital Services NHS Trust, Broomfield Hospital, Court Road, Chelmsford, CM1 7ET, UK and 3Radiotherapy Department, Colchester Hospital University NHS Foundation Trust, Essex County Hospital, Lexden Road, Colchester, CO3 3NB, UK Email: Alaaeldeen M Elbahaie* - [email protected]; Dia E Kamel - [email protected]; Julia Lawrence - [email protected]; Neville G Davidson - [email protected] * Corresponding author
Published: 9 November 2009 World Journal of Surgical Oncology 2009, 7:84
doi:10.1186/1477-7819-7-84
Received: 27 August 2009 Accepted: 9 November 2009
This article is available from: http://www.wjso.com/content/7/1/84 © 2009 Elbahaie et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Malignant Mesothelioma is a rare primary neoplasm affecting the serosal membranes. During its relative short course, this malignant neoplasm can give local and, rarely, distant haematogenous metastases in different organs. The reported metastatic sites include liver, lung, heart, brain, thyroid, adrenals, kidneys, pancreas, bone, soft tissue, skin and lymph nodes. Case Presentation: We report a sixty one year-old man with a history of malignant pleural epithelioid mesothelioma treated with six cycles of Pemetrexed and Carboplatin completed 03/11/ 04 followed by radiotherapy to the drain site 250 Kv/TD20Gy/5F completed 13/12/2004. Then he developed multiple facial skin lesions 4 years later. These lesions were proved to be metastatic malignant sarcomatoid mesothelioma. Conclusion: Mesothelioma metastases should be suspected in any known Mesothelioma patient with newly developed skin lesion.
Background
Case Presentation
Malignant Mesothelioma is a rare primary neoplasm affecting the serosal membranes. During its relative short course, this malignant neoplasm can give local and, rarely, distant haematogenous metastases in different organs. The reported metastatic sites include liver, lung, heart, brain, thyroid, adrenals, kidneys, pancreas, bone, soft tissue, skin and lymph nodes. The increased incidence of malignant mesothelioma and the improvement of survival rates due to the newly introduced chemotherapeutic agents bring to light the importance of studying its amended natural history.
A 61 year-old white man with known history of pleural mesothelioma on regular follow up was found to develop multiple facial skin lesions wi
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