Malignant Mesothelioma and Pseudomyxoma
This book covers different aspects of the rare neoplasms – malignant mesothelioma and pseudomyxoma peritonei. The monograph includes up-to-date information on etiology, pathogenesis and diagnostics of malignant mesothelioma and pseudomyxoma peritonei, as
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Malignant Mesothelioma and Pseudomyxoma
Malignant Mesothelioma and Pseudomyxoma
Mikhail V. Kiselevskiy • Amir G. Abdulaev Mikhail M. Davydov Editors
Malignant Mesothelioma and Pseudomyxoma
Editors Mikhail V. Kiselevskiy Laboratory of Cell Immunity N.N. Blokhin National Medical Research Center Moscow, Russia Mikhail M. Davydov Oncologist and Surgeon Thoracic Research Department N.N. Blokhin National Medical Research Center Moscow, Russia
Amir G. Abdulaev Oncologist and Surgeon Thoracic Research Department N.N. Blokhin National Medical Research Center Moscow, Russia
ISBN 978-3-319-99509-0 ISBN 978-3-319-99510-6 (eBook) https://doi.org/10.1007/978-3-319-99510-6 Library of Congress Control Number: 2018962371 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
Peritoneal pseudomyxoma and mesothelioma are rare tumors. Despite differences in their pathological structure, these malignancies have some common characteristics, such as lack of reliable diagnostic methods, predominantly peritoneal dissemination, rare lympho-hematogenous metastases, and a difficult choice of optimal treatment strategy. The lack of specific clinical diagnostic symptoms of peritoneal pseudomyxoma and mesothelioma and the rare incidence of these neoplasms cause diagnostic errors; therefore, an accurate interpretation of the histologic results is ultimately needed. Conventional therapy, such as systemic chemotherapy after diagnostic or symptomatic surgeries of mesothelioma, results in poor prognosis with median of survival of 6–15 months. Systemic therapy of pseudomyxoma peritonei is ineffective, while the volume of completed cytoreduction of pseudomyxoma and mesothelioma i
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