Late-onset post-lesional paroxysmal hypothermia: a case series and literature review

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Late‑onset post‑lesional paroxysmal hypothermia: a case series and literature review Perrine Devic1,2 · Laure Peter‑Derex3,4 · Aurélie Richard‑Mornas1,3 · Sylvie Ernesto5 · Pascale Nesme5 · François Mauguière1,3 · Syvain Rheims1,3  Received: 24 May 2020 / Revised: 17 June 2020 / Accepted: 18 June 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Background  Paroxysmal hypothermia (PH) is a rare condition characterized by recurrent episodes of spontaneous hypothermia, bradycardia, disorders of consciousness and, in some cases, hyperhidrosis. When associated with a detectable hypothalamic lesion, PH episodes usually occur shortly after the brain insult. Methods  We performed a retrospective study to identify patients who had demonstrated at least one episode of symptomatic spontaneous PH as defined by (i) tympanic temperature