Left atrial appendage closure in patients with a reduced left ventricular ejection fraction: results from the multicente
- PDF / 889,401 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 8 Downloads / 178 Views
ORIGINAL PAPER
Left atrial appendage closure in patients with a reduced left ventricular ejection fraction: results from the multicenter German LAARGE registry Christian Fastner1,2,3 · Johannes Brachmann4 · Thorsten Lewalter5 · Uwe Zeymer6 · Horst Sievert7,8 · Martin Borggrefe1,2,3 · Christian Weiß9 · Volker Geist10 · Alexander Krapivsky11 · Matthias Käunicke12 · Harald Mudra13 · Matthias Hochadel14 · Steffen Schneider14 · Jochen Senges14 · Ibrahim Akin1,2,3 Received: 23 October 2019 / Accepted: 4 March 2020 © The Author(s) 2020
Abstract Background Interventional left atrial appendage closure (LAAC) effectively prevents thromboembolic events in atrial fibrillation patients. Impaired left ventricular ejection fraction (LVEF) increases not only the thromboembolic risk but also the complication rates of cardiac interventions. The LAAC procedure’s benefit in patients with an impaired LVEF, therefore, has yet to be investigated. Methods LAARGE is a prospective, non-randomized registry depicting the clinical reality of LAAC in Germany. Procedure was conducted with different standard commercial devices, and follow-up period was one year. In the sense of an as-treated analysis, patients with started procedure and documented LVEF were selected from the whole database. Results 619 patients from 37 centers were categorized into one of three groups: LVEF > 55% (56%), 36–55% (36%), and ≤ 35% (8%). Prevalence of cardiovascular comorbidity increased with LVEF reduction (p
Data Loading...
