Improving reproducibility of left ventricular ejection fraction in pediatric oncology patients: less is more
- PDF / 1,316,816 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 28 Downloads / 187 Views
ORIGINAL PAPER
Improving reproducibility of left ventricular ejection fraction in pediatric oncology patients: less is more R. W. Loar1,5 · R. H. Pignatelli1,5 · H. P. Tunuguntla1,5 · N. C. Rainusso2,5 · M. M. Gramatges2,5 · J. C. Plana3,5 · C. V. Noel4,5 Received: 4 March 2020 / Accepted: 25 May 2020 © Springer Nature B.V. 2020
Abstract Reproducible measurement of left ventricular (LV) systolic function by echocardiography is important to detect cancer therapy-related cardiac dysfunction (CTRCD). We hypothesized that limiting the number of imaging operators and use of a single vendor would improve reproducibility of these measures. A standard operating procedure (SOP) whereby LV measurements were standardized and a cardio-oncology imaging team (5 sonographers, 6 cardiologists) was established. All pediatric oncology patient echocardiograms were acquired on a single vendor platform. In total, 100 consecutive pre-SOP and 100 post-SOP studies were reviewed. LV end-diastolic dimension (LVEDD), posterior wall thickness (PW), shortening fraction (SF), and ejection fraction by Simpson’s biplane (EF) were re-measured by 2 blinded readers, and compared to what was originally reported. Image quality was scored by number of LV segments imaged (grades 1–4). Inter-observer reproducibility pre/post-SOP was assessed with intra-class coefficient (α). Reducing the number of imaging operators improved image quality (Grade ≥ 3: 13% vs. 46%, p
Data Loading...
