Levodopa
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Lack of efficacy: case report A 69-year-old-woman exhibited lack of efficacy during treatment with levodopa for atypical parkinsonism. The woman presented for stiffness and allodynia in her left arm at the age of 67 years. Bradykinesia, hypomimia and rigidity in the limbs was noted upon examination. After two years, dystonia with myoclonic tremor and hyposthesia in the left arm was noted. Also, balance disorder and falls were observed. She was referred for urge incontinence, constipation and restless legs syndrome. She was diagnosed with atypical parkinsonism. She exhibited no response to levodopa treatment [route and dosage not stated]. After five years of the diagnosis, she died of progressive supranuclear palsy. Natera-Villalba E, et al. Beyond what the eyes can see, pathology holds the key. European Journal of Neurology 27 (Suppl. 1): 911 abstr. EPO2235, May 2020. Available 803498681 from: URL: https://onlinelibrary.wiley.com/journal/14681331 [abstract]
0114-9954/20/1819-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 29 Aug 2020 No. 1819
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