Lung ultrasound as diagnostic tool for SARS-CoV-2 infection
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Lung ultrasound as diagnostic tool for SARS‑CoV‑2 infection Giorgio Bosso1 · Enrico Allegorico1 · Antonio Pagano1 · Giovanni Porta1 · Claudia Serra1 · Valentina Minerva1 · Valentina Mercurio2 · Teresa Russo1 · Concetta Altruda1 · Paola Arbo1 · Chiara De Sio1 · Ferdinando Dello Vicario1 · Fabio Giuliano Numis1 Received: 7 May 2020 / Accepted: 16 September 2020 © Società Italiana di Medicina Interna (SIMI) 2020
Abstract The aim of this study was to explore the role of lung ultrasound (LUS) in the diagnosis of SARS-CoV-2 infection and to verify its utility in the prediction of lung disease’s severity and outcome. Fifty-three consecutive patients presenting to the Emergency Department of Santa Maria delle Grazie Hospital with high suspicion of SARS-CoV-2 infection underwent diagnostic test for SARS-CoV-2 on samples obtained from nasopharyngeal swab as well as complete proper diagnostic work-up that included clinical evaluation, laboratory tests, blood gas analyses, chest CT and LUS. A semiquantitative analysis of B-lines distribution was performed to calculate the LUS score. Patients were divided into two groups according to the results of both SARS-CoV-2 diagnostic test and other exams (Group A = pneumonia due to SARS-CoV2 infection vs Group B = no SARS-CoV2 infection and another definite diagnosis). LUS showed an excellent accuracy in predicting the diagnosis of SARS-CoV-2 infection (area under the ROC curve of 0.92 with a sensibility of 73% and a specificity of 89% a the cut-off of 12.5). LUS score was more impaired in SARS-CoV-2 patients (18.1 ± 6.0 vs 7.6 ± 5.9, p
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