Methionine Aminopeptidase: Structure and Function
Aminopeptidases (APs) that are capable of removing methionine esidues from the N-terminal end of peptides and proteins can broadly be grouped into two classes: those which are nonspecific and generally act processively, i.e., they remove other residues as
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AMINOPEPTIDASES Allen Taylor, Ph.D. Tufts University Boston, Massachusetts, U.S.A.
Springer-Verlag Berlin Heidelberg GmbH
MOLECULAR BIOLOGY lNTELLIGENCE UNIT AMINOPEPTIDASES R.G. LANDES COMPANY Austin, Texas, U.S.A. International Copyright © 1996 Springer-V erlag Berlin Heidelberg Softcover reprint of the hardcover 1st edition 1996 Ali rights reserved. No part of this book may be reproduced or tmnsmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher.
'Springer
While the authors, editors and publisher believe that drug selection and dosage and the specifications and usage of equipment and devices, as set forth in chis book, are in accord with current recommendations and practice at the time of publication, they make no warranty, expressed or implied, with respect to material described in this book. In view of the ongoing research, equipment development, changes in governmental regulations and the rapid accumulation of information relating to the biomedical sciences, the reader is urged to carefully review and evaluate the information provided herein. Library of Congress Cataloging-in-Publication Data Taylor, Allen, 1946Aminopeptidases 1 Allen Taylor. p.cm.- (Molecular biology intelligence unit) Includes bibliogmphical references and index. ISBN 978-3-662-21605-7 ISBN 978-3-662-21603-3 (eBook) DOI 10.1007/978-3-662-21603-3 1. Aminopeptidases. I. Title. II. Series. QQP609.A44T38 1996 572'.7548--dc21
96-47143 CIP
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DEDICATION To my mother who made every day of childhood wonderful, and to my father whose toil, idealism, devotion, and song nurtured us and whose memory is carved forever in our hearts. To friends, family and colleagues, without whom I would not have had the opportunity to do this book.
r.========== CONTENTS=========::;-] 1. Aminopeptidases, Occurrence, Regulation and Nomenclature ... 1 Allen Taylor Introduction ............................................................................
