Methods
In addition to hematological diagnosis based on the blood count, the hemoglobin, erythrocyte count, hematocrit, and the erythrocyte indices MCH (mean corpuscular hemoglobin), MCHC (mean corpuscular hemoglobin concentration), and MCV (mean corpuscular volu
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Ferritin in Iron Metabolism Diagnostic Strategies
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Springer-Verlag Wi en GmbH
M Wick, W Pinggera, and P Lehmann
Ferritin in Iron Metabolism Diagnostic Strategies
Springer- Verlag Wien GmbH
Dr. Manfred Wick Institute for Clinical Chemistry, Klinikum Grosshadem, University of Munich, Federal Republic of Germany
Prim. Univ.-Prof. Dr. WulfPinggera Internal Medicine, General Hospital, Arnstetten, Austria
Dr. Paul Lehmann Boehringer Mannheim GmbH, Mannheim, Federal Republic of Germany
Translation of Ferritin im EisenstoffWechsel- Diagnostische Strategien Wien-NewYork: Springer-Verlag 1991 © 1991 bYSpringer-VeriagWien Originally published by Springer-Verlag Wien-New York in 1991
ISBN 978-3-7091-4435-0 (eBook) ISBN 978-3-211-82324-8 DOI 10.1007/978-3-7091-4435-0 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machines or similar means, and storage in data banks. © 1991 by Springer-Verlag Wien Printed on acid-free paper Product Liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
With 23 Figures ISBN 978-3-211-82324-8
Foreword This book is based on papers presented by Dr. Wick and Prof. Pinggera during a Specialists' Conference sponsored by Boehringer Mannheim GmbH (Chairman: Prof. Wolfgang Vogt, Munich) in BemriediLake Stamberg in May 1990. It is a joint work by three authors. It seemed appropriate to divide the work, in view ofthe rapid development of clinical chemistry, together with the knowledge that medicine as a science is constantly in a state of flux and that it influences clinical practice. We have endeavored to describe clearly the relevance of the principal analytes of iron metabolism to early recognition, diagnosis, and the monitoring of therapy, as well as to provide useful bedside support for the doctor. The authors are grateful to Cheryl Byers of Boehringer Mannheim and to Thomas Schmuttermeier of Springer-Verlag for their committed cooperation and their expert support in the publication of this book. Doris Raab of Boehringer Mannheim has made a valuable contribution in preparing the diagrams.
November 1991
M. Wick W. Pinggera P. Lehmann
Table of Contents Introduction ....................................................................................... . Physiological Principles .... ........... .......... .......................... ..................
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Absorption of Iron .. ..... .............. ..... ...................
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