Methyl aminolevulinate
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Methyl aminolevulinate Pain: case report A 56-year-old man experienced pain while receiving methyl aminolevulinate [Metvix] to treat Buschke-Lowenstein tumour. The man was admitted to a dermatology inpatient ward with a rapidly growing Buschke-Lowenstein tumour of the anal region. He underwent topical photodynamic therapy, with application of 16% methyl aminolevulinate [dosage not stated] to the lesions, and 5–10mm of surrounding skin. After 3 hours, the lesion was irradiated. He reported a tingling pain during the first photodynamic therapy session [time to reaction onset not stated]. The man was given oral gabapentin during his second and third photodynamic sessions, and his pain was successfully controlled. Author comment: "Patients frequently report that photodynamic therapy illumination is accompanied by a burning sensation and stinging pain; these appear to be the most common complications. The mechanism of this pain if not fully understood, but nerve stimulation and tissue injury might be involved". Chu G-Y, et al. Buschke-Lowenstein tumor (giant condyloma acuminatum) successfully treated by topical photodynamic therapy: A case report. Dermatologica Sinica 31: 94-97, No. 2, Jun 2013. Available from: URL: http:// 803096213 dx.doi.org/10.1016/j.dsi.2012.08.003 - Taiwan
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Reactions 30 Nov 2013 No. 1480
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