Micromachines for Biological Micromanipulation
Provides new mechanical designs of microinjectors, microsyringes, microgrippers, and microforce sensors with experimental verifications; Presents new position and force control of the microinjection systems for biological cell microinjection; Examples giv
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Micromachines for Biological Micromanipulation
Micromachines for Biological Micromanipulation
Qingsong Xu
Micromachines for Biological Micromanipulation
123
Qingsong Xu Department of Electromechanical Engineering University of Macau Macau China
ISBN 978-3-319-74620-3 ISBN 978-3-319-74621-0 https://doi.org/10.1007/978-3-319-74621-0
(eBook)
Library of Congress Control Number: 2017964244 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To my family
Preface
Micromachines (or microrobots) refer to miniature devices (typical size in micrometer and millimeter scales) which are powered to produce motions or forces for performing an intended action. According to performance requirement, a micromachine can incorporate structural elements, actuators, sensors, control components, and interfaces to achieve a specific objective. Such devices have been extensively developed for various applications including biology, medical sciences, chemistry, energy, environmental sciences. Currently, biological micromanipulation emerges as an important approach in biomedical engineering. It concerns the manipulation of biological entities involving positioning, gripping, injecting, cutting, and fusion. In particular, the single cell (typical size around 10–500 µm) acts as the basic component of life, as it is the smallest unit of biological things. Therefore, biological cell micromanipulation has attracted extensive interests from both academia and industry in the past two decades. Micromachines are ideal tools for micromanipulation of biological entities due to the merit of size matching
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