Midazolam
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Midazolam Anaphylaxis: case report A 30-year-old man developed an anaphylactic reaction immediately after receiving midazolam [dosage, therapeutic indication and time to reaction onset not stated]. His reaction showed good response to an intensive medical management. A prick test with midazolam was positive and he developed an 8 × 5mm wheal and a 15 × 13mm erythema. An 11 × 11mm wheal and a 25 × 25 erythema developed following an intradermal test with flunitrazepam. An oral challenge test with diazepam 10mg showed no reaction. Author comment: "The type of reaction and its timing, as well as the skin test results are consistent with an IgEmediated reaction." Lizarza S, et al. Midazolam immediate allergy with diazepam tolerance. Allergy 62 801104973 (Suppl. 83): 541-542 abstr. 1579, 2007 - Spain
0114-9954/10/1194-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 22 Mar 2008 No. 1194
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