Minimum Allergen Screening Panel for Allergic Rhinitis in Bangalore: A Cross Sectional Study

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ORIGINAL ARTICLE

Minimum Allergen Screening Panel for Allergic Rhinitis in Bangalore: A Cross Sectional Study Rafees Hassan Palliyalthodi1,2 • Badari Datta1 • Anita Mariet Thomas1 • R. Kamala1 • Brinda A. Poojari1 • B. V. Manjula1 • Unmesh Warwantkar Rao1

Received: 24 September 2020 / Accepted: 10 November 2020 Ó Association of Otolaryngologists of India 2020

Abstract Allergic rhinitis (AR) is a very common condition presenting to an Otorhinolaryngologist. Prevalence of AR is on the increase and it has significant impact on quality of life of the patient. Skin prick test (SPT) is a simple test to determine allergen sensitization status in patients with AR. There is wide variation in allergen panel used in SPT among various allergy clinics and many centres use a large panel of allergens which requires multiple skin pricks for the patient undergoing the test. Our aim was to identify a minimum panel of allergens among patients with symptoms of AR undergoing SPT which could be used as a screening panel for AR. The present study is a cross sectional study in patients with symptoms of AR undergoing SPT at Allergy clinic of Bangalore Baptist hospital over a period of 18 months from January 2018. & Rafees Hassan Palliyalthodi [email protected] Badari Datta [email protected] Anita Mariet Thomas [email protected] R. Kamala [email protected] Brinda A. Poojari [email protected] B. V. Manjula [email protected] Unmesh Warwantkar Rao [email protected] 1

Department of ENT, Bangalore Baptist Hospital, Hebbal, Bangalore, India

2

NIBRAS, 38/919 A1, Athanikkal, Westhill, Calicut, Kerala 673005, India

149 patients were included in the study and 26 patients who had negative SPT for all allergens tested were excluded. Prevalence of sensitization for individual allergens was calculated. House dust mite (Dermatophagoides pteronyssinus and Dermatophagoides farinae) was the most prevalent allergen to which 73.9% and 65.8% of our study population was sensitized respectively. We identified a minimum allergen panel of 3 allergens (Dermatophagoides pteronyssinus, Lambs quarter and Dermatophagoides farinae) which could identify [ 90% of patients sensitized in the study group. Keywords Allergic rhinitis  Minimum allergen panel  Skin prick test  Allergen sensitization

Introduction Allergic rhinitis (AR) is a global health problem and its prevalence is on the increase [1, 2]. AR and associated bronchial asthma contributes a huge financial burden to health care system. It also affects lifestyle and productivity of individual. It has substantial impact on quality of life. It is considered one of the most prevalent non communicable disease. An estimated 400 million people suffer from AR [3]. AR affect 20% of the Indian population [4]. Many patients presenting with nasal symptoms may have coexistent AR and failure to identify and control this could be one of the causes for poor outcome of treatment. Skin prick test is a simple, cheap and safe test to determine the allergen sensitization status in AR patients.The