Molecular Allergy Diagnostics Using Multiplex Assays
The availability of single allergens and their use in microarray technology enables the simultaneous determination of specific IgE (sIgE) to a multitude of different allergens (>100) in a multiplex procedure requiring only minute amounts of serum. This
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Molecular Allergy Diagnostics Innovation for a Better Patient Management Forewords by Robert G. Hamilton and Stefan Vieths
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Molecular Allergy Diagnostics
Jörg Kleine-Tebbe • Thilo Jakob Editors
Molecular Allergy Diagnostics Innovation for a Better Patient Management
Foreword 1 by Robert G. Hamilton Foreword 2 by Stefan Vieths
Editors Jörg Kleine-Tebbe, MD Professor of Dermatology and Allergology Allergy and Asthma Center Westend Outpatient Clinic Hanf Ackermann and Kleine-Tebbe Berlin Germany
Thilo Jakob, MD Professor of Dermatology and Allergology Chairman of the Department of Dermatology and Allergology University Medical Center Gießen and Marburg, Campus Gießen Justus Liebig University Gießen Gießen Germany
ISBN 978-3-319-42498-9 ISBN 978-3-319-42499-6 (eBook) DOI 10.1007/978-3-319-42499-6 Library of Congress Control Number: 2016963214 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. The editors gratefully thank Thermo Fisher Scientific, Phadia AB, Uppsala, Sweden, for the educational grant provided supporting English translation and language revision. Based partially on the German language edition: Molekulare Allergiediagnostik by Jörg Kleine-Tebbe, Thilo Jakob. © Springer-Verlag Berlin Heidelberg 2015 Springer-Verlag is part of Springer Science+Business Media All Rights Reserved Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword 1
Since 1967, when immunoglobulin E (IgE) was identified as the reagin in the blood that could transfer allergic sensitization, allergists have been striving to achieve increasingly “allergen-specific” diagnoses to help their patients with more targeted management strategies. In the U
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