Molecular Control Mechanisms in Striated Muscle Contraction
Molecular Control Mechanisms in Striated Muscle Contraction addresses the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, as well as the modulation of these mechanisms by important (patho)physiological variables such
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Advances in Muscle Research Volume I
Series Editor GJ.M. Stienen, Vrije Universiteit, Amsterdam. The Netherlands
Molecular Control Mechanisms in Striated Muscle Contraction
Edited by
R. John Solaro University of Illinois at Chicago, Chicago, Illinois, U.S.A.
and
Richard L. Moss University of Wisconsin Medical School, Madison , Wisconsin, U.S.A.
Springer-Science+Business Media, B.Y.
A c.I.P. Catalogue record for this book is available from the Library of Congress.
ISBN 978-90-481-6069-3 ISBN 978-94-015-9926-9 (eBook) DOI 10.1007/978-94-015-9926-9
Printed on acid-free paper
All Rights Reserved
© SpringerScience+Business Media Dordrecht2002 Originallypublishedby KluwerAcademic Publishersin 2002. Softcoverreprint of the hardcover 1st edition 2002 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work .
We dedicate this volume to the memory of our colleague Dr. Rhea Levine - a superb experimentalist, an enthusiastic scientist, and a generous friend .
TABLE OF CONTENTS Page PREFACE
IX
INTRODUCTION Ger Stienen, Series Editor
XI
EXCITATION-CONTRACTION COUPLING IN SKELETAL MUSCLE A. Gonzalez & E. Rios EXCITATION-CONTRACTION COUPLING IN CARDIAC MUSCLE A.W. Trafford & D .A. Eisner
49
THE THICK FILAMENT OF VERTEBRATE STRIATED MUSCLE RJ.C. Levine & R.W. Kensler
91
STRUCTURE AND REGULATION OF CARDIAC AND SKELETAL MUSCLE THIN FILAMENTS L.S. Tobacman
143
CATION SIGNALING IN STRIATED MUSCLE CONTRACTION A.V. Gomes, K. Harada & J.D . Potter
163
CALCIUM-INDUCED MOLECULAR AND STRUCTURAL SIGNALING IN STRIATED MUSCLE CONTRACTION H.C. Cheung
199
COOPERATIVITY IN THE Ca 2+-REGULATION OF SKELETAL MUSCLE CONTRACTION M.A. Geeves & S.S . Lehrer
247
REGULATION OF THE RATE OF FORCE DEVELOPMENT IN HEART AND SKELETAL MUSCLES R.L. Moss, D.P . Fitzsimons & M.V. Razumova
271
MODULATION OF THIN FILAMENT ACTIVITY IN LONG AND SHORT TERM REGULATION OF CARDIAC FUNCTION RJ . Solaro, B.M .Wolska, G. Arteaga, A.F. Martin, P. Buttrick & P.Detombe
291
Vll
viii TABL E O F CONTE NTS THIN FILAMENT REG ULATION IN DEV ELOPM ENT P. Anderson
329
TH E FRANK-STARLING RELATIONSHIP : CELLULAR AN D MOLECULAR MECHANISMS F. Fuch s
379
DETERMINANTS OF UNLOAD ED SHORT EN ING VELOCITY IN STRIATED MUSCLE E. Hamsher
417
AUTHOR INDEX
443
COLOR SECTION
445
PREFACE Nowhere in biology is the marriage of structure and function as well expressed or understood as in the case of molecules that regulate the contraction and relaxation of striated muscles. In assembling what is known about these molecules, we have focused first on the processes that mediate Ca 2 + transients in both cardiac and skeletal muscles and then on the processes that translate the Ca 2+ signal to mechanical activity.
