Sliding Filament Mechanism in Muscle Contraction Fifty Years of Rese
Sliding Filament Mechanism in Muscle Contraction: Fifty Years of Research covers the history of the sliding filament mechanism in muscle contraction from its discovery in 1954 by H.E. Huxley through and including modern day research. Chapters in
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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan Recent Volumes in this Series Volume 557 BRAIN REPAIR Edited by M. Biihr Volume 558 DEFECTS OF SECRETION IN CYSTIC FIBROSIS Edited by Carsten Schultz Volume 559 CELL VOLUME AND SIGNALING Edited by Peter K. Lauf and Norma C. Adragna Volume 560 MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION X: Innate Immunity Edited by Sudhir Gupta, William Paul, and Ralph Steinman Volume 561 CHEMISTRY AND SAFETY OF ACRYLAMIDE IN FOOD Edited by Mendel Friedman and Don Mottram Volume 562 CHOLINERGIC MECHANISMS Edited by Jose Gonzalez-Ros Volume 563 UDPDATES IN PATHOLOGY Edited by David C. Chhieng and Gene P. Siegal Volume 564 GLYCOBIOLOGY AND MEDICINE Edited by John S. Axford Volume 565 SLIDING nLAMENT MECHANISM IN MUSCLE CONTRACTION: Fifty Years of Research Edited by Haruo Sugi
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SLIDING FILAMENT MECHANISM IN MUSCLE CONTRACTION Fifty Years of Research Edited by
Haruo Sugi Teiko University Tokyo, Japan
Sprin ger
Proceedings of the 2004 Tokyo Muscle Symposium, "Sliding Filament Mechanism in Muscle Contraction: Fifty Years of Research," held in Tokyo, Japan, March 7-10, 2004. ISSN: 0065 2598 ISBN-10: 0-387-24989-3 (Hardbound) ISBN-13: 978-0387-24989-6
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PREFACE
Fifty years have passed since the monumental discovery that muscle contraction resuhs from relative sliding between the thick filaments, consisting mainly of myosin, and the thin filaments, consisting mainly of actin (A.F. Huxley and Niedergerke, Nature 173; 971-973, 1954; H.E, Huxley and Hanson, Nature 173: 973-976, 1954). Until the early 1970's, considerable progress have been achieved in the research field of muscle contraction. For example, A.F. Huxley an
