Molecular Genetics of Asthma
Presenting topics from the basic application of molecular genetics to more complex gene expression analysis using different models of study, this detailed volume explores asthma through the lens of genetics, considered to play an essential role in th
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María Isidoro-García Editor
Molecular Genetics of Asthma
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Molecular Genetics of Asthma Edited by
María Isidoro-García Department of Clinical Biochemistry, University Hospital of Salamanca, Salamanca, Spain; Department of Medicine, University of Salamanca, Salamanca, Spain; Salamanca Institute for Biomedical Research, IBSAL, Salamanca, Spain
Editor María Isidoro-García Department of Clinical Biochemistry University Hospital of Salamanca Salamanca, Spain Department of Medicine University of Salamanca Salamanca, Spain Salamanca Institute for Biomedical Research IBSAL, Salamanca, Spain
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-3650-2 ISBN 978-1-4939-3652-6 (eBook) DOI 10.1007/978-1-4939-3652-6 Library of Congress Control Number: 2016940979 © Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC New York
Preface Asthma is a multifactorial disease characterized by bronchial hyperresponsiveness and inflammation associated with airway obstruction episodes. Genetics is considered to play an essential role in the etiopathogenesis of the disease. The aim of this book is to provide the scientific community with a useful resource to study the molecular genetics in asthma. This book will guide the reader from the basic application of molecular genetics to the more complex gene expression analysis by using different models of study. Since asthma is a complex disease, this book is designed in six different sections to provide a review of the most useful techniques with examples of their applications in specific laboratory protocols.
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