Molecules, Systems and Signaling in Liver Injury
This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and d
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Wen-Xing Ding Xiao-Ming Yin Editors
Molecules, Systems and Signaling in Liver Injury
Cell Death in Biology and Diseases
Series Editors Xiao-Ming Yin Zheng Dong
More information about this series at http://www.springer.com/series/8908
Wen-Xing Ding • Xiao-Ming Yin Editors
Molecules, Systems and Signaling in Liver Injury
Editors Wen-Xing Ding Department of Pharmacology Toxicology and Therapy The University of Kansas Medical Center Kansas City, KS, USA
Xiao-Ming Yin Health Pathology Laboratory Indiana University Indianapolis, IN, USA
Cell Death in Biology and Diseases ISBN 978-3-319-58105-7 ISBN 978-3-319-58106-4 (eBook) DOI 10.1007/978-3-319-58106-4 Library of Congress Control Number: 2017945288 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Series Preface
Cell death, or conversely cell survival, is a major biological phenomenon. Just as with cell proliferation and cell differentiation, cell death is a choice that a cell has to make, sometimes voluntarily, other times accidentally. As such, cell death serves a purpose in the biology of a multicellular organism. The machinery of cell death and that of cell protection are evolutionarily conserved, and their elements can even be found in single-celled organism. The disruption of cell death mechanisms can often cause developmental abnormalities. Factors that can trigger cell death are diverse, and the cell death process is intricately connected with other biological processes. Cell death directly contributes to the pathogenesis of many diseases, including cancer, neurodegenerative diseases, and tissue injury in organ failure. The study o
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