Morphine

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Nausea: case report In a retrospective, case-control study of 40 patients, who underwent trans-axillary thoracic outlet decompression (TATOD) in the Netherlands between May 2018 and October 2018, a patient [age and sex not stated] was described, who developed nausea during treatment with morphine for post-operative pain. The patient, who had thoracic outlet syndrome, was admitted for TATOD. As per the standard protocol, after obtaining IV access, the patient received paracetamol [acetaminophen], and general anaesthesia was induced [specific drugs not stated]. Thereafter, the patient underwent TATOD using pectoral nerve blocks type 2 (PECS 2) anaesthesia technique and received ropivacaine [ropivacaine hydrochloride] injection in the pectoralis minor muscle. The patient was given granisetron and dexamethasone as prophylaxis against postoperative nausea and vomiting during the surgery. At the postsurgical care unit (PACU), the patient was treated with IV boluses of morphine 1 mg/mL for post-operative pain. However, the patient subsequently developed nausea, which was attributed to morphine [duration of treatment to reaction onset and outcome not stated]. Goeteyn J, et al. Interfascial Plane Blocks Reduce Postoperative Pain and Morphine Consumption in Thoracic Outlet Decompression. Annals of Vascular Surgery 66: 301-308, 803499076 Jul 2020. Available from: URL: http://doi.org/10.1016/j.avsg.2019.12.005

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Reactions 5 Sep 2020 No. 1820