Morphometry of the Human Lung
The work presented in this monograph marks a new era, we believe, both in the development of quantitative anatomy of the lung, and in the correlation of anatomy with physiology. For many years, physiologists interested in the overall functioning of the lu
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Ewald R.Weibel, M. D. Research Associate, Department of Cytology, The Rockefeiler Institute, New York, N. Y. Formerly Research Associate, Department of Medicine, College of Physicians and Surgeons, Columbia University, and The Cardiopulmonary Labaratory of The Chest Service, Bellevue Hospital, New York, N. Y.
With a Foreword by
Andre F. Cournand, M. D. and
Dickinson W. Richards, M. D. College of Physicians and Surgeons, Columbia University, New York, N. Y.
With 109 Figures
Springer-Verlag Berlin Heidelberg GmbH 1963
All rights reserved, especiaJly that of translation into foreign languages. It is also forbidden to reproduce this book, either whole or in part, by photomechanlcal means (photostat. microfllm and{or microcard) without written permission from the Publishers ~ by Springer-Verlag Berlin Heidelberg 1963 Originally published by Springer Verlag OHG Berlin Goltigen Heidelberg in 1963. Softcover reprint of the hardcover I st edition 1963 Library of Congress Catalog Card Number 63-19191
ISBN 978-3-642-87555-7 ISBN 978-3-642-87553-3 (eBook) DOI 10.1007/978-3-642-87553-3
The use of general descriptive names, trade names, trade marks etc. in this publication, even if the former are not especially identifled, is not to be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used free1y by anyone
C'est a vous, eher maitre, Que je voue cet oeuvre. Vos pensees en etaient les racinesPar votre genie lui pousseront des fleurs. J'espere que Je tronc et les tiges vous plaisent.
TO MY MASTER AND FRIEND
DOMINGO M. GOMEZ
Foreword The work presented in this monograph marks a new era, we believe, both in the development of quantitative anatomy of the lung, and in the correlation of anatomy with physiology. For many years, physiologists interested in the overall functioning of the lung have felt a need for better quantitative descriptions of pulmonary anatomy. As physiologists, we know a good deal about the forces operating to producepulmonary ventilation, and the quantities that define this function in rest and exercise ; and the same for effective distribution of air within the lung - "alveolar" ventilation-, and for the exchange of respiratory gases between air and blood. There have been no correspondingly precise quantitative measurements of the pulmonary structures that serve theese functions. The great advances in the study of pulmonary anatomy in the past decade have been chiefly in the realm of "fine structure". This has tended to bring together anatomy and biochemistry or physical chemistry, rather than anatomy and physiology. This conjunction has aided, for example, the conception of diffusion as a physicochemical process, but not that of diffusion as a metabolic bodily function. It was, therefore, a remarkably fortunate circumstance which brought together in our laboratory, about three years ago, Professor DoMINGO GoMEZ and Dr. EWALD R. WEIBEL: Professor GoMEZ a mathematician and biophysicist of distinction and long experience; Dr. WEIBEL a youn
