Muse Cells
Multilineage-differentiating stress-enduring (Muse) cells were first reported in 2010. Since then, multiple groups have elucidated their unique properties. Muse cells are non-tumorigenic endogenous pluripotent-like stem cells that express pluripotency gen
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Jeffrey M. Gimble · Darja Marolt Presen Richard O. C. Oreffo · Susanne Wolbank · Heinz Redl Editors
Cell Engineering and Regeneration
Reference Series in Biomedical Engineering Tissue Engineering and Regeneration Series Editor Heinz Redl Ludwig Boltzmann Institute for Experimental and Clinical Traumatology/AUVA Research Center Austrian Cluster for Tissue Regeneration Wien, Austria
This series Tissue Engineering and Regeneration consists of comprehensive reference texts encompassing the biological basis of tissue regeneration, basic principles of tissue engineering, and the current state-of-the-art in tissue engineering of specific tissues and organs. Each volume combines established fundamentals and the latest developments, thus forming an invaluable collection for both experienced researchers as well as practitioners from other areas of expertise. The spectrum of topics ranges from the use of cells for tissue regeneration and tissue engineering, growth factors and biological molecules affecting tissue development and regeneration, to the specific roles of biophysical factors in tissue development and regeneration. Tissue engineering lies at the crossroads of medicine, life sciences, and engineering. The field has developed extensively over the last two decades, addressing the requirements of tissue and organ replacement as well as regeneration in a variety of congenital, traumatic, disease, and aging-related conditions, including some of the most critical unmet challenges in modern medicine. Both our increased understanding of the biological basis of tissue engineering as well as significant technological advances mean that engineering design principles can now be used for the de novo construction of functional tissue replacements that meet the requirements of research and clinical applications. More information about this series at http://www.springer.com/series/13441
Jeffrey M. Gimble • Darja Marolt Presen Richard O. C. Oreffo • Susanne Wolbank Heinz Redl Editors
Cell Engineering and Regeneration With 86 Figures and 17 Tables
Editors Jeffrey M. Gimble Tulane Univ. Sch. of Medicine New Orleans, LA, USA
Darja Marolt Presen AUVA Trauma Research Center Ludwig Boltzmann Institute for Experimental and Clinical Traumatology Vienna, Austria Austrian Cluster for Tissue Regeneration Vienna, Austria
Richard O. C. Oreffo Bone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences University of Southampton Southampton, UK
Susanne Wolbank AUVA Trauma Research Center Ludwig Boltzmann Institute for Experimental and Clinical Traumatology Vienna, Austria Austrian Cluster for Tissue Regeneration Vienna, Austria
Heinz Redl AUVA Trauma Research Center Ludwig Boltzmann Institute for Experimental and Clinical Traumatology Vienna, Austria Austrian Cluster for Tissue Regeneration Vienna, Austria
ISBN 978-3-319-08830-3 ISBN 978-3-319-08831-0 (eBook) ISBN 978-3-319-08832-7 (print and electronic bundle) https://doi.org/10.1007/978-3-319-08831-0 © Springer Nature S
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