Myocardial tissue tagging with cardiovascular magnetic resonance
- PDF / 1,184,199 Bytes
- 12 Pages / 610 x 792 pts Page_size
- 31 Downloads / 238 Views
BioMed Central
Open Access
Review
Myocardial tissue tagging with cardiovascular magnetic resonance Monda L Shehata1, Susan Cheng2, Nael F Osman1, David A Bluemke3 and João AC Lima*2 Address: 1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA, 2Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA and 3Department of Radiology, National Institutes of Health, Bethesda, MD, USA Email: Monda L Shehata - [email protected]; Susan Cheng - [email protected]; Nael F Osman - [email protected]; David A Bluemke - [email protected]; João AC Lima* - [email protected] * Corresponding author
Published: 21 December 2009 Journal of Cardiovascular Magnetic Resonance 2009, 11:55
doi:10.1186/1532-429X-11-55
Received: 23 April 2009 Accepted: 21 December 2009
This article is available from: http://www.jcmr-online.com/content/11/1/55 © 2009 Shehata et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Cardiovascular magnetic resonance (CMR) is currently the gold standard for assessing both global and regional myocardial function. New tools for quantifying regional function have been recently developed to characterize early myocardial dysfunction in order to improve the identification and management of individuals at risk for heart failure. Of particular interest is CMR myocardial tagging, a non-invasive technique for assessing regional function that provides a detailed and comprehensive examination of intra-myocardial motion and deformation. Given the current advances in gradient technology, image reconstruction techniques, and data analysis algorithms, CMR myocardial tagging has become the reference modality for evaluating multidimensional strain evolution in the human heart. This review presents an in depth discussion on the current clinical applications of CMR myocardial tagging and the increasingly important role of this technique for assessing subclinical myocardial dysfunction in the setting of a wide variety of myocardial disease processes.
Introduction Heart failure (HF) is the result of advanced myocardial dysfunction and continues to be a leading cause of morbidity and mortality in developed nations. In the United States alone, an estimated 5.3 million adults carry the diagnosis of HF and the disease prevalence continues to escalate with aging of the population. In addition to conferring a significant burden of illness to affected individuals, management of HF also imposes enormous expense to the health care system [1]. Therefore, the ability to identify individuals at risk for developing HF - those who might benefit from targeted preventive interventions would be of immense value. To this end, some of the most promising approaches to improved risk stratification involve u
Data Loading...
