National Institute of Allergy and Infectious Diseases, NIH Volume 3:

National Institute of Allergy and Infectious Diseases, NIH: Volume III: Intramural Research contains a broad overview of the research activity of the NIAID intramural scientists working in the Division of Intramural Research (DIR) and the Vaccine Research

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Infectious Disease Vassil St. Georgiev

For further volumes, go to www.springer.com/series/7646

National Institute of Allergy and Infectious Diseases, NIH 

Volume 3 Intramural Research

Edited by Vassil St. Georgiev, PhD

Office of Global Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

Foreword by Kathryn C. Zoon, PhD

Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

Editor Vassil St. Georgiev Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases Bethesda, MD USA [email protected]

ISBN 978-1-60761-511-8 e-ISBN 978-1-60761-512-5 DOI 10.1007/978-1-60761-512-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010930847 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)

Foreword

The huge biomedical research enterprise that today is the National Institutes of Health traces its roots to 1887 and a small bacteriology lab on Staten Island. As they had been for centuries, infectious diseases were still the scourge of public health, and this lab marked the federal government's first efforts to study contagious diseases, hygiene, and public health. By the end of the 1930s, the lab had become the National Institute of Health and had relocated about 10 miles from the White House to Bethesda, Maryland. Since then, NIH has grown and been shaped by new health threats and new opportunities to address them. Today, NIH's 27 institutes, organized around threats (infections, cancer), opportunities (genomics), and anatomy (heart, lung, blood) conduct and support research in every area of biomedicine. In addition to Bethesda, many of these institutes have government laboratories in other regions of the USA and around the world. These volumes represent the work of investigators in one of NIH's largest institutes, the National Institute of Allergy and Infectious Diseases (NIAID). As the infectious diseases institute, we claim that very first NIH lab as our own. Dr. Joseph Kinyoun directed the lab, then called the Hygienic Laboratory, from 1887 to 1899. His research in bac