Neonatal Tumours

All those physicians and surgeons who have responsibility for newborn infants will face the problem of dealing with tumours. Neonatal Tumours is an authoritative, comprehensive and complete account of the various tumours encountered in infancy. It reviews

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Prem Puri (Ed.) With assistance from Rajendra Surana

Neonatal Tumours With 54 Figures

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Springer

Prem Puri MS, FACS Consultant Paediatric Surgeon Our Lady's Hospital for Sick Children National Children's Hospital The Children's Hospital, Dublin and Director of Research Children's Research Centre Our Lady's Hospita1.for Sick Children Dublin, Ireland

ISBN-13:978-1-447 1-3030-7 British Library Cataloguing in Publication Data Neonatal Tumours I. Puri, Prem II. Surana, Rajendra 618.92994 ISBN-13:978-1-4471-3030-7 e-ISBN-13:978-1-4471-3028-4 DOl: 10.1007/978-1-4471-3028-4

Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may only be reproduced, stored or transmitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency. Enquiries concerning reproduction outside those terms should be sent to the publishers. ©Springer-Verlag London Limited 1996 Softcover reprint of the hardcover 1st edition 1996 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore free for general use. Product liability: The publishers can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Typesetting: EXPO Holdings, Malaysia 28/3830-543210 Printed on acid-free paper

Preface

Neonatal tumours comprise 2% of paediatric tumours. Although uncommon, these tumours form an interesting group for a number of reasons. There are differences in type, incidence, natural history and response to therapy from those of apparently similar tumours seen in older children. Until recently, genetic factors have been implicated in many congenital tumours, but during the last few years, the effect of the environment on the pathogenesis of these tumours has been gaining much attention. Neonatal tumours, because of their short exposure to environmental factors, offer new avenues to the understanding of the pathogenesis of these tumours. This book is intended for those who have a clinical responsibility for newborn babies. It provides an authoritative, comprehensive and complete account of the various tumours that can be found in the neonate. It reviews the epidemiology of neonatal tumours, the genetic association and clinical features of tumours, their recognition and management. It is designed to cover the entire spectrum of neonatal tumours.