Neural Mechanisms of Anesthesia
Although anesthetics have been used successfully for over 150 years, their mechanisms of action are little understood, a fact that significantly limits our ability to design new and safer agents. In Neural Mechanisms of Anesthesia, leading investigators c
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ontemporary linical • eurosclence
Series Editors:
Ralph Lydic and Helen A. Baghdoyan
Genetics and Genomics. of Neurobehavioral Disorders edited by Gene S. Fisch, 2003 Sedation and Analgesia for Diagnostic and Therapeutic Procedures edited by Shobha Malviya, Norah N. Naughton, and Kevin K. Tremper, 2003 Neural Mechanisms of Anesthesia, edited by Joseph F. Antognini, Earl E. Carstens, and Douglas E. Raines, 2003 Glutamate and Addiction edited by Barbara Herman, 2002 Molecular Mechanisms of Neurodegenerative Diseases edited by Marie-Franfoise Chesselet, 2000
NEURAL MECHANISMS OFANEsrnEsIA Edited by
JOSEPH
F. ANTOGNINI,
MD
University ofCalifornia at Davis School ofMedicine, Davis, CA
EARL CARSTENS,
PhD
University ofCalifornia at Davis School ofMedicine, Davis, CA
DOUGLAS
E.
RAINES, MD
Harvard Medical School and Massachusetts General Hospital, Boston, MA
SPRINGER SCIENCE+BUSINESS MEDIA,LLC
© 2003 Springer Science+Business Media New York Originally published by Humana Press Inc. in 2003 Softcover reprint of the hardcover 1st edition 2003
www.humanapress.com All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. All authored papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time of publication. Notwithstanding, as new research, changes in government regulations, and knowledge from clinical experience relating to drug therapy and drug reactions constantly occurs, the reader is advised to check the product information provided by the manufacturer of each drug for any change in dosages or for additional warnings and contraindications. This is of utmost importance when the recommended drug herein is a new or infrequently used drug. It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients. Further it is the responsibility of the health care provider to ascertain the Food and Drug Administration status of each drug or device used in their clinical practice. The publisher, editors, and authors are not responsible for errors or omissions or for any consequences from the application of the information presented in this book and make no warranty, express or implied, with respect to the contents in this publication.
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