Noise-Induced Hearing Loss Scientific Advances
Exposure to loud noise continues to be one of the largest causes of hearing loss in the adult population, already affecting some 15 percent of Americans between the ages of 20 and 69. There have been a number of discoveries and advances that have increase
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 Perspectives on Noise-Induced Hearing Loss ...................................... Colleen G. Le Prell and Donald Henderson
 
 Part I 2
 
 3
 
 Noise-Induced Hearing Loss: Scope of the Problem
 
 The Public Health Significance of Noise-Induced Hearing Loss ........................................................................................... Peter M. Rabinowitz
 
 13
 
 Noise-Induced Hearing Loss and Tinnitus: Challenges for the Military ................................................................... Marjorie A. M. Grantham
 
 27
 
 Part II
 
 4
 
 1
 
 Relationship Between Noise Exposure and Resulting Anatomical, Physiological, and Perceptual Changes in Hearing
 
 The Use of Kurtosis Measurement in the Assessment of Potential Noise Trauma ..................................................................... Donald Henderson and Roger P. Hamernik
 
 41
 
 5
 
 Noise-Induced Structural Damage to the Cochlea.............................. Bohua Hu
 
 57
 
 6
 
 Neural Coding of Sound with Cochlear Damage ................................ Eric D. Young
 
 87
 
 7
 
 Suprathreshold Auditory Processing in Noise-Induced Hearing Loss ........................................................................................... Mini N. Shrivastav
 
 8
 
 The Neurobiology of Noise-Induced Tinnitus ..................................... James A. Kaltenbach and Ryan Manz
 
 137 151
 
 ix
 
 x
 
 Contents
 
 Part III 9
 
 10
 
 11
 
 Genes That Influence Susceptibility to Noise-Induced Hearing Loss ........................................................................................... Tzy-Wen Gong and Margaret I. Lomax
 
 179
 
 Effects of Early Noise Exposure on Subsequent Age-Related Changes in Hearing................................................................................ Eric C. Bielefeld
 
 205
 
 Effects of Exposure to Chemicals on Noise-Induced Hearing Loss ........................................................................................... Thais C. Morata and Ann-Christin Johnson
 
 223
 
 Part IV 12
 
 13
 
 14
 
 Susceptibility and Factors Contributing to NIHL
 
 Protection and Repair
 
 Hearing Protection Devices: Regulation, Current Trends, and Emerging Technologies .................................................................. John G. Casali
 
 257
 
 Prevention of Noise-Induced Hearing Loss: Potential Therapeutic Agents................................................................ Colleen G. Le Prell and Jianxin Bao
 
 285
 
 Frontiers in the Treatment of Hearing Loss ........................................ Tatsuya Yamasoba, Josef M. Miller, Mats Ulfendahl, and Richard A. Altschuler
 
 339
 
 Index ................................................................................................................
 
 369
 
 Contributors
 
 Richard A. Altschuler Department of Otolaryngology and Department of Cell & Developmental Biology, Kresge Hearing Research Institute, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5616, USA [email protected] Jianxin Bao Department of Otolaryngology, Washington University, 4560 Clayton Avenue, St. Louis, MO 63110, USA [email protected] Eric C. Bielefe		
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