Normal, Transformed and Leukemic Leukocytes A Scanning Electron Micr
The scanning electron microscope (SEM) has been used with increasing frequency in recent years to study the surface mor phology of normal, transformed and malignant leukocytes. Since the original reports on critical point-dried lymphocytes published in 1
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Normal, Transformed and Leukemic Leukocytes A Scanning Electron Microscopy Atlas
With 236 Figures
Springer-Verlag Berlin Heidelberg New York 1977
AARON POLLIACK, M.D. Associate Professor of Medicine Department of Hematology Hadassah University Hospital and Hebrew University Hadassah Medical School Jerusalem, Israel
ISBN-13: 978-3-642-66727-5 e-ISBN-13: 978-3-642-66725-1 DOl: 10.1007/978-3-642-66725-1 Library of Congress Cataloging in Publication Data. Polliack, Aaron. 1939. Normal, . Includes index. 1. Leukemiatransformed and leukemic leucocytes. Bibliography: p. Atlases. 2. Leukocytes-Atlases. 3. Cell transformation-Atlases. 4. Cancer cells-Atlases. 5. Scanning electron microscope-Atlases. I. Title. RC643.P63 616.1'55'00222 77-14223 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law, where copies are made for other than private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement wIth the publisher.
© by Springer-Verlag Berlin Heidelberg 1977. Softcover reprint of the hardcover I st edition 1977 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
This book is gratefully dedicated to my wife LILY for her assistance and constant encouragement
Preface
The scanning electron microscope (SEM) has been used with increasing frequency in recent years to study the surface morphology of normal, transformed and malignant leukocytes. Since the original reports on critical point-dried lymphocytes published in 1973, results of other studies using improved methods have been reported giving rise to some controversy in this field and this is discussed in the text of the atlas. Advances in preparatory techniques recorded during the past 3 years have also contributed much to a better understanding of cell surface phenomena as seen under the SEM. The text of the atlas traces the developments in this field chronologically, summarizes the available literature and presents the current situation in the light of the most recent studies in this field. The photographs were selected to illustrate the spectrum of surface morphology of the different cell types obtained from normal individuals and patients with disease states. Hopefully, the atlas will serve as a guide for future studies and as an illustration of what SEM has to offer in providing details of surface architecture. In an advancing field such as this in which new methods of cell preparation coupled with vast movements in the resolution of the microscope will no doubt produce better results, atlases run the risk of becoming outdated quite quickly. Nevertheless an overall review need
