Obesity: Pathology and Therapy
Obesity is a serious medical problem that affects millions of people, especially in Western societies. Although long considered a complicating factor in a variety of diseases, there is now widespread agreement that obesity itself should be classified and
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Obesity: Pathology and Therapy Contributors P. Bjorntorp, S.R. Bloom, I.E. Blundell, C Bouchard,
CF. Burant, L.A. Campfield, IF. Caro, Y.C Chagnon, M. DiGirolamo, V. Drapeau, I Dwyer, B.I. Goldstein, IG. Granneman, I.CG. Halford, B.C Hansen, 1.B. Harp, M.D. Hirvonen, R.E. Keesey, I W. Kolaczynski, R. Konikoff, Y. Ma, K. G. MacDonald, D.E. Moller, L. Perusse, F.X. Pi-Sunyer, W.I. Pories, M. Rossi, D.M. Smith, F.I. Smith, I Stevens, M.E. Trautmann, A. Tremblay, A.A. Truett, L.H.T. Van der Ploeg, D.B. West, B. York
Editors:
D.H. Lockwood and T.G. Heffner
Springer
DEAN H. LOCKWOOD, M.D.
Vice President Department of Clinical Research Parke-Davis Pharmaceutical Research Division of Warner Lambert Company 2800 Plymouth Road Ann Arbor, MI 48105 USA THOMAS
C.
HEFFNER, PH.D.
Sr. Director, Neuroscience Therapeutics Parke-Davis Pharmaceutical Research Division of Warner Lambert Company 2800 Plymouth Road Ann Arbor, MI 48105 USA e-mail: [email protected] With 60 Figures and 42 Tables lSBN-13: 978-3-642-64070-4 e-lSBN-13: 978-3-642-59651-3 DOl: 10.1007/978-3-642-59651-3
Library of Congress Cataloging-in-Publication Data Obesity: pathology and therapy/contributors, P. Bjorntorp ... [et a1.1; editors D.H. Lockwood and T.G. Heffner. p. cm. - (Handbook of experimental pharmacology; v. 149) Includes bibliographical references and index. ISBN-13: 978-3-642-64070-4 1. Obesity. I. Bjorntorp, Per. II. Lockwood, Dean H. III. Heffner, T.G. (Thomas G.), 1949- IV. Series. QP905.H3 vol. 149 [RC628] 615'.1 s - dc21 [616.3'98] 00-044025 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for Prosecution under the German Copyright Law. Springer-Verlag Berlin Heidelberg New York a member of BertelsmannSpringer Science+Business Media GmbH © Springer-Verlag Berlin Heidelberg 2000 Softcover reprint of the hardcover 1st edition 2000 The use of general descriptive names, registered names, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: design & production GmbH, Heidelberg Typesetting: Best-set Typesetter Ltd., Hong Kong SPIN: 10666361
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Preface
Obesity is a
