OCT in Central Nervous System Diseases The Eye as a Window to the Br

This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promis

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OCT in Central Nervous System Diseases

Andrzej Grzybowski • Piero Barboni Editors

OCT in Central Nervous System Diseases The Eye as a Window to the Brain

Editors Andrzej Grzybowski Professor of Ophthalmology Head of Ophthalmology Department

Poznan City Hospital Poznan Poland

Piero Barboni Studio Oculistico d’Azeglio Bologna Italy

Chair of Department of Ophthalmology University of Warmia and Mazury Olsztyn

Poland

ISBN 978-3-319-24083-1 ISBN 978-3-319-24085-5 DOI 10.1007/978-3-319-24085-5

(eBook)

Library of Congress Control Number: 2015956209 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Contents

1

Introduction: Retina Imaging – Past and Present . . . . . . . . . . . . . . . Andrzej Grzybowski and Piero Barboni

1

2

OCT Technique – Past, Present and Future . . . . . . . . . . . . . . . . . . . . Tigran Kostanyan, Gadi Wollstein, and Joel S. Schuman

7

3

Optical Coherence Tomography and Optic Nerve Edema. . . . . . . . . Kendra A. Klein and Thomas R. Hedges III

35

4

OCT and Compressive Optic Neuropathy. . . . . . . . . . . . . . . . . . . . . . Mário Luiz Ribeiro Monteiro

69

5

Optical Coherence Tomography (OCT) and Multiple Sclerosis (MS) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Rachel C. Nolan, Kannan Narayana, Laura J. Balcer, and Steven L. Galetta

87

6

OCT and Parkinson’s Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Shahnaz Miri, Sofya Glazman, and Ivan Bodis-Wollner

105

7

Optical Coherence Tomography in Alzheimer’s Disease . . . . . . . . . . Gianluca Coppola, Vincenzo Parisi, Gianluca Manni, Francesco Pierelli, and Alfredo A. Sadun

123

8

Friedreich’s Ataxia and More: Optical Coherence Tomography Findings in Rare Neurological Syndromes . . . . .