Omics Approaches to Understanding Muscle Biology
This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcrip
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Jatin George Burniston Yi-Wen Chen Editors
Omics Approaches to Understanding Muscle Biology
Methods in Physiology Published on behalf of The American Physiological Society by Springer
Methods in Physiology This series describes experimental techniques in cellular, molecular and general physiology. Each book is edited by experts in their field and covers theory and history behind the method, critical commentary, major applications with examples, limitations and extensions of each technique, and vital future directions. More information about this series at http://www.springer.com/series/11781
Jatin George Burniston • Yi-Wen Chen Editors
Omics Approaches to Understanding Muscle Biology
Editors Jatin George Burniston Research Institute for Sport and Exercise Sciences Liverpool John Moores University Liverpool, Merseyside, UK
Yi-Wen Chen Children’s National Health System George Washington University Washington, DC, USA
Methods in Physiology ISBN 978-1-4939-9801-2 ISBN 978-1-4939-9802-9 https://doi.org/10.1007/978-1-4939-9802-9
(eBook)
© The American Physiological Society 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Science+Business Media, LLC, part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Contents
1
The Role of Omics Approaches in Muscle Research . . . . . . . . . . . . Stefano Schiaffino, Carlo Reggiani, and Marta Murgia
Part I 2
Genomic and Epi-genomic
Genome-Wide Association Studies in Muscle Physiology and Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Luca Bello, Elena Pegoraro, and Eric P. Hoffman
3
Chromatin Epigenomics in Muscle Development and Disease . . . . . Jelena Perovanovic
4
Guidelines for Bioinformatics and the Statistical Analysis of Omic Data .
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