Onco-Cardiology: Consensus Paper of the German Cardiac Society, the German Society for Pediatric Cardiology and Congenit
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CONSENSUS PAPER
Onco‑Cardiology: Consensus Paper of the German Cardiac Society, the German Society for Pediatric Cardiology and Congenital Heart Defects and the German Society for Hematology and Medical Oncology Tienush Rassaf1 · Matthias Totzeck1 · Johannes Backs2 · Carsten Bokemeyer3 · Michael Hallek4 · Denise Hilfiker‑Kleiner5 · Andreas Hochhaus6 · Diana Lüftner7 · Oliver J. Müller8 · Ulrich Neudorf9 · Roman Pfister10 · Stephan von Haehling11 · Lorenz H. Lehmann12 · Johann Bauersachs5 on behalf of Committee for Clinical Cardiovascular Medicine of the German Cardiac Society Received: 12 March 2020 / Accepted: 13 March 2020 © The Author(s) 2020
Abstract The acute and long-lasting side effects of modern multimodal tumour therapy significantly impair quality of life and survival of patients afflicted with malignancies. The key components of this therapy include radiotherapy, conventional chemotherapy, immunotherapy and targeted therapies. In addition to established tumour therapy strategies, up to 30 new therapies are approved each year with only incompletely characterised side effects. This consensus paper discusses the risk factors that contribute to the development of a potentially adverse reaction to tumour therapy and, in addition, defines specific side effect profiles for different treatment groups. The focus is on novel therapeutics and recommendations for the surveillance and treatment of specific patient groups. Keywords Cardio-oncology · Cardiotoxicity · Survivorship programs · Cancer therapy · Chemotherapy Lorenz H. Lehmann and Johann Bauersachs have contributed equally to this work. This consensus paper is published in English in “Clinical Research in Cardiology” (DOI 10.1007/s00392-020-01636-7) and in German in “Der Kardiologe” (DOI 10.1007/s12181-020-00395-z) simultanously. * Tienush Rassaf tienush.rassaf@uk‑essen.de 1
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Centre Essen, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany
2
Institute for Experimental Cardiology, University Hospital Heidelberg, Heidelberg, Germany
3
Department of Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Centre for Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany
4
Department I of Internal Medicine, Center for Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany
5
Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany
6
Department of Hematology and Medical Oncology, University Hospital Jena, Jena, Germany
7
Department of Haematology, Oncology and Tumour Immunology, Charité, Humboldt University Berlin, Berlin, Germany
8
Department of Internal Medicine III (Cardiology, Angiology and Internal Intensive Care Medicine), University Hospital Schleswig-Holstein, University of Kiel, Kiel, Germany
9
Department of Pediatrics III, West German Heart and Vascular Centre Essen, University Hospital Essen, Essen, Germany
10
Clinic III for Internal Me
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