Open or Minimally Invasive Resection for Oesophageal Cancer?
Oesophagectomy is one of the most challenging surgical operations. Potential for morbidity and mortality is high. Minimally invasive techniques have been introduced in an attempt to reduce postoperative complications and recovery times. Debate continues o
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Abstract
Oesophagectomy is one of the most challenging surgical operations. Potential for morbidity and mortality is high. Minimally invasive techniques have been introduced in an attempt to reduce postoperative complications and recovery times. Debate continues over whether these techniques decrease morbidity and whether the quality of the oncological resection is compromised. Globally, minimally invasive oesophagectomy (MIO) has been shown to be feasible and safe, with outcomes similar to open oesophagectomy. There are no controlled trials comparing the outcomes of MIO with open techniques, just a few comparative studies and many single institution series from which assessments of the current role of MIO have been made. The reported improvements of MIO include reduced blood loss, shortened time in high dependency care and decreased length of hospital stay. In comparative studies there is no clear reduction in respiratory complications, although larger series suggest that MIO may have a benefit. Although MIO approaches report less lymph node retrieval compared with open extended lymphadenectomy, MIO cancer outcomes are comparable. MIO will be a major component of the future oesophageal surgeons’ armamentarium, but should continue to be carefully assessed.
C. Mariette (&) W. B. Robb Department of Digestive and Oncological Surgery, University Hospital Claude Huriez, Lille, France e-mail: [email protected] C. Mariette University of Lille 2, Lille, France C. Mariette Inserm, UMR837, Team 5 Mucins, epithelial differentiation and carcinogenesis, JPARC, Rue Michel Polonovski, 59045 Lille cedex, France
F. Otto and M. P. Lutz (eds.), Early Gastrointestinal Cancers, Recent Results in Cancer Research 196, DOI: 10.1007/978-3-642-31629-6_10, Ó Springer-Verlag Berlin Heidelberg 2012
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Randomized trials comparing MIO versus open resection in oesophageal cancer are urgently needed: two phase III trials are recruiting, the TIME and the MIRO trials.
Contents 1 Introduction.......................................................................................................................... 2 MIO Techniques .................................................................................................................. 3 Results.................................................................................................................................. 4 MIO Learning Curve........................................................................................................... 5 Comments and Future ......................................................................................................... References..................................................................................................................................
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Introduction
With increasing experience and skills at performing laparoscopic and thoracoscopic surgery in the past decade, minimally invasive oesophagectomy (MIO) is increasingly being used for sur
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