Osteoporosis in Older Persons Advances in Pathophysiology and Therap

This second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this

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Osteoporosis in Older Persons Advances in Pathophysiology and Therapeutic Approaches Second Edition

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Osteoporosis in Older Persons



Gustavo Duque • Douglas P. Kiel Editors

Osteoporosis in Older Persons Advances in Pathophysiology and Therapeutic Approaches Second Edition

Editors Gustavo Duque, MD, PhD, FRACP Australian Institute for Musculoskeletal Science The University of Melbourne and Western Health St Albans, VIC Australia

Douglas P. Kiel, MD, MPH Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School Boston, MA USA Director Musculoskeletal Research Center

Institute for Aging Research Hebrew SeniorLife Boston, MA USA

ISBN 978-3-319-25974-1    ISBN 978-3-319-25976-5 (eBook) DOI 10.1007/978-3-319-25976-5 Library of Congress Control Number: 2016934851 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland

To my lovely and devoted parents, Maximo and Rubiela, who always inculcated in me the humility to respect the feeble, the curiosity to understand nature and the respect for God who is the Great Architect of everything that is described in this book. Gustavo Duque, MD, PhD, FRACP In memory of my mother, Adrienne Kiel, who inspired me to pursue a career in medicine and to dedicate my research to the study of osteoporosis, which she lived with until she passed away following a hip fracture. Douglas P. Kiel, MD, MPH



Acknowledgements

The Editors would like to thank Ms. Julia Megginson for her assistance in the preparation of this work. We remain grateful to Mrs. Melissa Morton from Springer for her outstanding support on this project and for her understanding that older adults suffer from a particular syndrome that must be understood and treated. Finally, we would like to thank all the authors of these book chapters who, l