Paroxetine
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Paroxetine Bruxism successfully treated with tandospirone in an elderly patient: case report An 81-year-old man, who had previously received sulpiride, started receiving paroxetine 10mg at bedtime for major depressive disorder. After 7 days, his paroxetine dosage was increased to 20 mg/day and, at 14-day follow-up, the dosage was further increased to 30 mg/day. At 21-day follow-up, he reported sore teeth and jaws, and ‘night-and-day jaw clenching’. He started receiving tandospirone and, within 1 week, the clenching had stopped and his sore teeth and jaws had improved. Author comment: "This case adds to the literature by suggesting that [serotonin reuptake inhibitor]-induced bruxism can be treated with tandospirone, a 5-HT1A receptor agonist." Kishi Y. Paroxetine-induced bruxism effectively treated with tandospirone Journal of Neuropsychiatry and Clinical Neurosciences 19: 90-91, No. 1, Feb 2007 801070671 Japan
0114-9954/10/1146-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 7 Apr 2007 No. 1146
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