Patho-Epigenetics of Infectious Disease
Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitu
- PDF / 3,924,640 Bytes
- 150 Pages / 504.63 x 737.01 pts Page_size
- 71 Downloads / 213 Views
Janos Minarovits Hans Helmut Niller Editors
PathoEpigenetics of Infectious Disease
Advances in Experimental Medicine and Biology Volume 879 Editorial Board Irun R. Cohen, The Weizmann Institute of Science, Rehovot, Israel N.S. Abel Lajtha, Kline Institute for Psychiatric Research, Orangeburg, NY, USA John D. Lambris, University of Pennsylvania, Philadelphia, PA, USA Rodolfo Paoletti, University of Milan, Milan, Italy
More information about this series at http://www.springer.com/series/5584
Janos Minarovits • Hans Helmut Niller Editors
Patho-Epigenetics of Infectious Disease
Editors Janos Minarovits University of Szeged Szeged, Hungary
Hans Helmut Niller University of Regensburg Regensburg, Germany
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-24736-6 ISBN 978-3-319-24738-0 (eBook) DOI 10.1007/978-3-319-24738-0 Library of Congress Control Number: 2015957434 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Foreword
During recent years, the study of epigenetic phenomena in genetics has attracted increasing interest in all fields of biology and medicine. In epigenetics, we are dealing with a gamut of regulatory mechanisms based on the methylation of DNA, multiple histone modifications, the activity of small RNA’s, and additional, so far, incompletely understood biochemical reactions. While there is solid evidence to support the role of these functions as participants in the regulation of genetic activities, it remains to be elucidated which modulations epigenetic regulators are subject to. Today, epigenetic mechanisms are held at least partly responsible for the causation of: • Complex human diseases (from tumor to psychiatric) with evident or surmised genetic background
Data Loading...
