Microbial Endocrinology Interkingdom Signaling in Infectious Disease

About this book Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. It is the intent of this book to introduce a new perspective to the current unde

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Mark Lyte    Primrose P.E. Freestone ●

Editors

Microbial Endocrinology Interkingdom Signaling in Infectious Disease and Health

Editors Mark Lyte Texas Tech University Health Sciences Center Lubbock, TX USA [email protected]

Primrose P.E. Freestone Department of Infection, Immunity and Inflammation University of Leicester School of Medicine Leicester UK [email protected]

ISBN 978-1-4419-5575-3 e-ISBN 978-1-4419-5576-0 DOI 10.1007/978-1-4419-5576-0 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010922891 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

About the Editors

Prof. Mark Lyte, Ph.D., M.S., MT(ASCP) is a Professor in the Department of Pharmacy Practice, School of Pharmacy and adjunct Professor in the Departments of Internal Medicine and Microbiology and Immunology, School of Medicine of Texas Tech University Health Sciences Center. Professor Lyte obtained his Ph.D. and M.S. degrees from the Weizmann Institute of Science in Israel. His undergraduate degree in the clinical laboratory sciences and work as a board-certified medical technologist in the hospital setting have influenced his translational approach throughout his career. Early work investigating the ability of stress to modulate immunity during infection led Professor Lyte to examine the role of bacterial recognition of stress-related neuroendocrine hormones in the infective process. This research ultimately led him in 1992 to establish the field of microbial endocrinology. In addition to having served on scientific review panels for the National Institutes of Health and other worldwide agencies, Professor Lyte has been awarded the Joseph Susman Memorial Award for Surgical Infectious Disease Research by the Surgical Infection Society and was named a finalist for the NIH Director’s Pioneer Award. Dr. Primrose Freestone, B.Sc. (Hons), Ph.D., PGCE is a Lecturer in Clinical Microbiology, in the Department of Infection, Immunity and Inflammation, School of Medicine, University of Leicester. She has been a close collaborator of Professor Mark Lyte for over 10 years and is a foundation contributor in the field of microbial endocrinology. A microbial biochemist by training, Dr Freestone was the first to ide