Patient-Specific Induced Pluripotent Stem Cell Models Generation and
This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug dev
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Andras Nagy Kursad Turksen Editors
Patient-Specific Induced Pluripotent Stem Cell Models Generation and Characterization
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, UK
For further volumes: http://www.springer.com/series/7651
Patient-Specific Induced Pluripotent Stem Cell Models Generation and Characterization
Edited by
Andras Nagy Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada
Kursad Turksen Ottawa Hospital Research Institute, Ottawa, ON, Canada
Editors Andras Nagy Lunenfeld-Tanenbaum Research Institute Toronto, ON, Canada
Kursad Turksen Ottawa Hospital Research Institute Ottawa, ON, Canada
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-3033-3 ISBN 978-1-4939-3034-0 (eBook) DOI 10.1007/978-1-4939-3034-0 Library of Congress Control Number: 2015951804 Springer New York Heidelberg Dordrecht London # Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Humana Press is a brand of Springer Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
Preface Rapid developments in the field of induced pluripotent stem (iPS) cells have provided novel opportunities and approaches, both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases. To complement our volume on methods for establishing iPS cells, we have also collected representative protocols on various disease models. We are grateful to all the contributors who shared the details of their protocols for this volume; without their generous efforts, this volume would not have been possible. Dr. John Walker, Editor in Chief of Methods in Molecular Biology, was instrumental in getting this volume off the ground, and we thank him for it. Patrick Marton, Editor of Springer
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