Peptide-Based Materials
Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and
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A Activated monomer (AM), 4 Amido-amidate nickelacycles, 7 Amine initiators, 5 Amine-hydrochloride initiators, 11 Amino acids, 1 N-2-(Aminoethyl)-3aminopropyltrimethoxysilane, 93 b-Amyloid, 43, 146 Arginine–glycine–aspartic acid (RGD), 137 Arthropod cuticle, resilin, 94 Artificial extracellular matrix (aECM), 91 Aspartimides, 36 ATRP, 93, 139
B Bait peptides, 64 Biomaterials, 135 Biomimicry, 137, 154, 157 Block copolymers, 1 Block copolypeptides, 14 Blood, synthetic, 130 Bone morphogenetic proteins (BMPs), 89
C Cell-penetrating peptide (CPP), 87 Co-assembly, 27 Collagen, 102 Copolypeptides, 14 Core–shell CdSe/CdS nanoparticles, 16 Cu(I)-catalyzed azide-alkyne cycloaddition click chemistry, 93 Cyclisation, 36 Cytotoxicity, 129
D Deprotection, 19, 34, 121 Dicyclohexylcarbodiimide (DCC), 32 Diketopiperazines, 36 Dipeptides, 152 Dityrosine, 99 DNA delivery, 130 Docetaxel, 129 DOX-loaded hyaluronan-b-poly(g-benzyl glutamate), 130 Doxorubicin, 85, 119, 129 Drug delivery, 84, 117, 135 Drug depots, 89
E Elastin, 71, 73, 155 Elastin-binding protein (EBP), 74 Elastin-derived peptides (EDP), 76 Elastin-like polypeptides, 71, 155 Encapsulation, 117, 129, 140 Enhanced permeability and retention (EPR), 129
F Fibrils, mixed, 46 Fibrinogen, 144 Fibroblast growth factor (FGF), 107, 154 9-Fluorenylmethoxycarbonyl (Fmoc) group, 32 Fluorescein isothiocyanate (FITC), 130 Fmoc-RGD tripeptides, 152 Functionalization, 27
G Glutenin, 102 Group-transfer polymerization (GTP), 13 169
170 H Hemoglobin, encapsulated, 130 Hexafluoroisopropanol, 60 Hexamethyldisilazane (HMDS), 12 Hyaluronan, 129 Hydrogels, 135, 139 crosslinks, 141 elastin-like polypeptide-based, 155 PEG, 157 peptide amphiphiles, 153 self-healing, 150 b-sheet, 152 Hydrogen bonds, 147 1-Hydroxy-7-azabenzotriazole (HOAt), 32 1-Hydroxybenzotriazole (HOBt), 32 N-(2-Hydroxypropyl)methacrylamide (HPMA), 159 N-Hydroxysuccinimide (HOSu), 32 Hyperthermia, 86
I Immobilization, 140 Indocyanine green (ICG), 130 Insulin fibrils, 50 Inverse transition cycling (ITC) purification, 81 Isocyanocarboxylates, 10
L Liposomes, 119 Lysyl oxidase, 76
M Matrix metalloproteinases (MMP), 158 Membrane translocating sequence (MTS), 87 Microfibrils, 75 Molecular dynamics, 27 Molecular self-assembly, 143 Monodansylcadaverine, 62 mPEG-b-poly(L-lysine)-b-palmitoyl, 130 Muscle, 108
N Nanocarriers, 88 Native chemical ligation (NCL), 121 Native extracellular matrix (ECM), 137 N-carboxyanhydrides (NCAs), 1, 122, 138, Nickelacycle initiators, 7
Index O Organic–inorganic hybrids, 157 Oxazolone, 34
P PAMAM dendron-poly(L-lysine) block, 123 PEGylation, 157 Peptide amphiphiles (PAs), 151 Peptide piperidines, 36 Peptide-diacetylene b-sheet, 59 PICsomes, 129 Poly(amino acid) hydrogels, 135 Poly(b-benzyl-L-aspartate), 20 Poly(g-benzyl-L-glutamate) (PBLG), 8, 124 Poly(ethylene glycol) (PEG), 8, 53, 124 PolyHIPE, 93 Poly(hydroxyalkyl glutamines), water-soluble, 17 Poly(N-isopropylacrylamide)-b-polylysine, 123 Poly(L-lysine)-block-poly(L-cysteine) block copolypeptides, 15 Poly(sarcosine), 130 Poly(VPGVG), 78 Polym
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