Percutaneous ablation of functioning adrenal adenoma: a report on 11 cases and a review of the literature

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Abdominal Imaging

Abdom Imaging (2013) DOI: 10.1007/s00261-013-9995-6

Percutaneous ablation of functioning adrenal adenoma: a report on 11 cases and a review of the literature Thiago Franchi Nunes,1,5 Denis Szejnfeld,1 Ana Carolina Wanderley Xavier,2 Claudio Elias Kater,2 Fabio Freire,3 Cassio Andreoni Ribeiro,4 Suzan Menasce Goldman1 1

Department of Diagnostic Imaging, Universidade Federal de Sa˜o Paulo (UNIFESP), Rua Napolea˜o de Barros, 800 Vila Clementino, Sa˜o Paulo, SP 04024-000, Brazil 2 Steroid Laboratory, Division of Endocrinology, UNIFESP, Rua Pedro de Toledo, 781/13 Vila Clementino, Sa˜o Paulo, SP 04039-032, Brazil 3 Division of Clinical Medicine, Department of Medicine, UNIFESP, Rua Pedro de Toledo, 920 Vila Clementino, Sa˜o Paulo, SP 04039-002, Brazil 4 Division of Urology, Department of Surgery, UNIFESP, Rua Napolea˜o de Barros, 715/2 Vila Clementino, Sa˜o Paulo, SP 04024-002, Brazil 5 Rua Borges Lagoa, 908/211 Vila Clementino, Sa˜o Paulo, SP CEP 04038-002, Brazil

Abstract Purpose: Percutaneous ablation of functioning adrenal adenomas has been an alternative to videolaparoscopic treatment. This study aimed to evaluate the feasibility, safety and efficacy of radiofrequency ablation (RFA) in the treatment of functioning adrenal tumors using a computed tomography (CT)-guided percutaneous technique as demonstrated by our experience and the literature. Methods: Eleven adult patients (mean age 46 years) with a diagnosis of functioning adrenal adenoma underwent CT-guided RFA between October 2011 and August 2012. All RFA procedures were performed using a needle electrode with a single lateral filament and the RITAÒ 1500X radiofrequency generator. The RFA protocol consisted of two cycles of 5 min each with 1-min interval, with no additional ablation cycles. Contrast-enhanced CT scans were obtained and analyzed for immediate treatment success and possible complications. Results: Maximum tumor dimension ranged from 1.2 to 3.4 cm. The mean procedure time was 74 min, and length of hospital stay ranged from 0.9 to 3.2 days (mean 1.8 days). One patient had residual pneumothorax and

Correspondence to: Thiago Franchi Nunes; email: thiagofranchinunes@ gmail.com

one patient had neuritis involving the T10 dermatome. Of 11 patients, 10 recovered from their condition. Only one patient remained with hyperaldosteronism, but with reduced anti-hypertensive medication. Conclusions: CT-guided percutaneous RFA was a safe and effective treatment for functioning adrenal adenomas, with short hospital length of stay and low complication rate. Key words: Ablation—Radiofrequency—Adrenal adenoma—Computed tomography

Laparoscopic resection is an established treatment for benign adrenal lesions [1]. Most functioning adenomas are represented by primary hyperaldosteronism (PH) and Cushing’s syndrome (CS). Reported complication rates range from 3.2 % to 20 % and include the occurrence of hemorrhage, damage to adjacent organs and/or structures (e.g., spleen), surgical wound infection, cardiac complications (postoperative myocardial infar