Performance of a semiconductor SPECT system: comparison with a conventional Anger-type SPECT instrument
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ORIGINAL ARTICLE
Performance of a semiconductor SPECT system: comparison with a conventional Anger-type SPECT instrument Yasuyuki Takahashi • Masao Miyagawa Yoshiko Nishiyama • Hayato Ishimura • Teruhito Mochizuki
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Received: 29 January 2012 / Accepted: 26 August 2012 / Published online: 6 September 2012 Ó The Author(s) 2012. This article is published with open access at Springerlink.com
Abstract Objective The performance of a new single photon emission computed tomography (SPECT) scanner with a cadmium-zinc-telluride (CZT) solid-state semiconductor detector (Discovery NM 530c; D530c) was evaluated and compared to a conventional Anger-type SPECT with a dual-detector camera (Infinia). Methods Three different phantom studies were performed. Full width at half maximum (FWHM) was measured using line sources placed at different locations in a cylindrical phantom. Uniformity was measured using cylindrical phantoms with 3 different diameters (80, 120, and 160 mm). Spatial resolution was evaluated using hotrod phantoms of various diameters (5, 9, 13, 16, and 20 mm). Three different myocardial phantom studies were also performed, acquiring projection data with and without defects, and evaluating the interference of liver and gallbladder radioactivity. In a clinical study, the D530c employed list-mode raw data acquisition with electrocardiogram (ECG)-gated acquisition over a 10-min period. From the 10-min projection data, 1-, 3-, 5-, 7- and 10-min SPECT images were reconstructed.
Y. Takahashi (&) Department of Nuclear Medicine Technology, Gunma Prefectural College of Health Sciences, 323-1 Kamioki-cho, Maebashi 371-0052, Japan e-mail: [email protected] M. Miyagawa Y. Nishiyama T. Mochizuki Department of Radiology, Ehime University Graduate School of Medicine, Toon, Japan H. Ishimura Department of Radiological Technology, Ehime University Hospital, Toon, Japan
Results The FWHM of the D503c was 1.73–3.48 mm (without water) and 3.88–6.64 mm (with water), whereas the FWHM of the Infinia was 8.17–12.63 mm (without water) and 15.48–16.28 mm (with water). Non-uniformity was larger for the D530c than for the Infinia. Truncation artifacts were also observed with the D530c in a U160 mm phantom. The contrast ratio, as defined by myocardial defect/non-defect ratio, was better for the D530c than for the Infinia, and the influence from liver and gallbladder radioactivities was less. Quantitative gated SPECT (QGS) software demonstrated significant differences between data captured over a 10-min period, relative to those acquired over periods of \5 min; there was no difference between ejection fractions calculated using data capture for periods C5 min (p \ 0.05). Conclusions The D530c is superior to the Infinia, with regard to both spatial resolution and sensitivity. In this study, these advantages were confirmed by the myocardial phantom and in a clinical setting, using the QGS software. Keywords Semiconductor camera Spatial resolution Sensitivity Myocardial SPECT
Introduction A recently released semiconductor d
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