PET/CT and PET/MR in Soft Tissue Sarcoma and Melanoma Patients: What to Image and How to Image It
In the evaluation of soft tissue sarcomas (STSs) and melanoma, hybrid imaging modalities such as F-18 FDG PET/CT and PET/MRI, which combine functional and anatomical images, have become extremely useful. These hybrid modalities, with the use of fluorine-1
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PET/CT and PET/MR in Melanoma and Sarcoma
Amir H. Khandani Editor
PET/CT and PET/MR in Melanoma and Sarcoma
Editor Amir H. Khandani Department of Radiology, UNC School of Medicine Division of Molecular Imaging and Therapeutics (Mit) Chapel Hill, NC USA
ISBN 978-3-030-60428-8 ISBN 978-3-030-60429-5 (eBook) https://doi.org/10.1007/978-3-030-60429-5 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To my beautiful, talented and accomplished wife, Romina, for all her love and support. For taking a journey across continents to allow me to pursue my career. To our daughters, Hannah and Sienna. Thank you for the endless joy and the love you bring to my life every day. To my mother, Parvin, for enduring separation after I left home at a young age in search of a new life and a new future. To my late father, Abbas, for his dedication to the education of his children. To my uncle Mahmoud and my aunt Cornelia for giving me the opportunity for new possibilities. To many mentors throughout my career for teaching me nuclear medicine and caring for the sick.
Preface
The purpose of this book is: 1. To serve as a comprehensive guide for imaging specialists for patient preparation as well as image acquisition and image interpretation in PET/ CT and PET/MR in general and specifically as they relate to melanoma and sarcoma. 2. To illustrate for referring physicians the role of PET/CT and PET/MR in patient management in melanoma and sarcoma from the surgeon’s and oncologist’s point of view. 3. To cover biological and physical underpinning of PET with FDG and other novel radiotracer with reference to melanoma and sarcoma and in general. 4. For a large portion o
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