Polymer Nanoparticles for Nanomedicines A Guide for their Design, Pr
Nanomedicines comprise a wide range of nanotechnologies including various types of nanoparticles developed as therapeutic, diagnostic and theranostic agents. The translation of nanoparticles in the clinical setting is rapidly progressing. It is now a quit
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lymer Nanoparticles for Nanomedicines A Guide for their Design, Preparation and Development
Polymer Nanoparticles for Nanomedicines
Christine Vauthier Gilles Ponchel •
Editors
Polymer Nanoparticles for Nanomedicines A Guide for their Design, Preparation and Development
123
Editors Christine Vauthier Institut Galien Paris Sud, Faculty of Pharmacy CNRS, University of Paris-Sud, University Paris Saclay 92296, Châtenay-Malabry Cedex France
ISBN 978-3-319-41419-5 DOI 10.1007/978-3-319-41421-8
Gilles Ponchel Institut Galien Paris Sud, Faculty of Pharmacy CNRS, University of Paris-Sud, University Paris Saclay 92296, Châtenay-Malabry Cedex France
ISBN 978-3-319-41421-8
(eBook)
Library of Congress Control Number: 2016951658 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
Polymers are macromolecules composed of many repeated subunits of different nature, leading to a broad range of compositions and properties. Both synthetic and natural polymers play a major role in the life sciences. Whereas natural polymers (nucleic acids, proteins, peptides) are the building blocks of biological structures and functions and are the support of genetic and epigenetic events, the polymerization of monomers through various modern synthetic routes (e.g., controlled anionic or radical polymerization, ring-opening polymerization, etc.) enables the design of synthetic polymers with unique physicochemical properties, including robustness, viscoelasticity, and a tendency to form glasses and semicrystalline structures rather than crystals. They may be combined to form tailor-made supramolecular architectures. The versatility of these polymer structures and the resulting properties offer many applications in the medical
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