Porcine dermal patches as a risk factor for recurrence after congenital diaphragmatic hernia repair
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ORIGINAL ARTICLE
Porcine dermal patches as a risk factor for recurrence after congenital diaphragmatic hernia repair Irene de Haro Jorge1 · Jordi Prat Ortells1 · Oriol Martín‑Solé1 · Elena Muñoz Fernandez1 · Africa Pertierra2 · Alba Martin‑Lluis1 · Xavier Tarrado1 Accepted: 16 November 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose Recurrence of congenital diaphragmatic hernia (CDH) is a treatment-related morbidity which can be preventable. There is no consensus about the ideal material for diaphragmatic substitution. The aim of our study is to identify if the use of porcine dermis patches increases the risk of CDH recurrence. Methods Retrospective review of medical records of CDH patients treated between 2013 and 2017 in our center was carried out. Demographic, clinical and surgical variables were collected. Regression analysis was performed to identify which factors increase the risk of recurrence. Results 50 patients entered the study. 94% of the patients had a left CDH, mean observed/expected lung-to-head ratio was 46%. 17 patients underwent a primary closure, the rest a patch closure: 25 Gore-Tex® and 8 porcine dermis patches were used. Seven patients presented recurrence (14%). Median follow-up time was 3.5 years (1.2–6.2). Univariate analysis revealed that the use of a porcine dermis patch (75%) increased the risk of recurrence compared with Gore-Tex® patch (4%) and primary closure (0%) p
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