Weight gain velocity and adequate amount of nutrition for infants with congenital diaphragmatic hernia

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ORIGINAL ARTICLE

Weight gain velocity and adequate amount of nutrition for infants with congenital diaphragmatic hernia Keita Terui1 · Yuko Tazuke2 · Kouji Nagata3 · Miharu Ito4 · Hiroomi Okuyama2 · Masahiro Hayakawa4 · Tomoaki Taguchi3 · Yasunori Sato5 · Noriaki Usui6 Accepted: 6 November 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  Growth retardation is a severe morbidity in infants with congenital diaphragmatic hernia (CDH). This study aimed to determine when catch-up growth starts in infants with CDH and to determine the adequate amount of nutrition required during catch-up growth. Methods  This was a multicenter retrospective cohort study involving neonates with isolated CDH (born 2006–2010; n = 98). Weight gain velocity (WGV) was calculated using body weight Z-scores. The minimum required weight gain was defined as WGV ≥ 0. Patients were dichotomized into severe and non-severe cases according to diaphragmatic defects. Results  Average monthly WGV changed from